Clarium, the creator of the world’s first AI-driven healthcare supply chain resiliency platform, announced a $27 million Series A funding round led by Northzone, with participation from General Catalyst, AlleyCorp, Kaiser Permanente Ventures, Texas Medical Center Ventures, and 1984 Ventures. The round brings Clarium’s total funding to $43 million, fueling its mission to optimize hospital supply chains amid rising economic and environmental uncertainties.

The healthcare sector wastes over $25 billion annually on supply chain inefficiencies, driven by fragmented data, outdated workflows, and wasted supplies. With intensifying risks from weather events, pandemics, and tariffs, these vulnerabilities threaten hospital operations nationwide.

Clarium’s platform, Astra OS, unifies crowdsourced data from providers, suppliers, and vendors, using AI to predict disruptions from real-time weather, geopolitical, and event data. It offers tailored substitution recommendations, streamlines workflows, and optimizes inventory management. Developed with input from leading health systems, Astra OS has delivered average cost savings of $10 million per hospital system, with 50% faster disruption resolution and 88% substitute approval rates.

“The healthcare supply chain’s inefficiencies burden hospitals under increasing financial strain,” said Steve Liou, Clarium’s Founder and CEO. “Our AI-driven platform, built with health systems, cuts waste, boosts productivity, and enhances patient outcomes. We’re grateful for Northzone and our investors’ support as we scale to more partners.”

“Clarium’s technology has transformed how we manage our supply chain,” said Jacqueline Epright, Chief Supply Chain Officer at Yale New Haven Health. “Their innovative, responsive approach helps us save costs and prioritize patient care.”

The $27 million investment will accelerate Astra OS development, expand Clarium’s team, and forge new health system partnerships.